Agent of mischief

Rhabdoid tumors are among the most recalcitrant childhood cancers, and scientists have long sought ways to understand what drives their resilience and makes them impervious to treatment. Now researchers have uncovered a molecular chain of events that interferes with a key mechanism that regulates cell behavior and controls tumor formation.

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Study raises concern of significant under-reporting of child abuse within US Army

Only 20 percent of medically diagnosed child abuse and neglect cases in US Army dependent children had a substantiated report with the Army's Family Advocacy Program, which investigates and treats child abuse. This rate is less than half of the rate of medically diagnosed child abuse cases substantiated by civilian Child Protective Services. Researchers say this contrast raises questions about the Army-reported rates of child abuse.

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Researchers identify biochemical mechanism behind a rare, painful genetic disease

A team of researchers has uncovered a possible biochemical mechanism behind a rare, painful genetic disorder called ACDC disease, which causes calcium buildup in the arteries. The finding could lead to the first effective treatment for the potentially debilitating condition and might provide insight into other vascular diseases, including atherosclerosis, the researchers say.

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Scientists unravel mechanism fueling growth of aggressive Rhabdoid tumors

Rhabdoid tumors are among the most recalcitrant childhood cancers, and scientists have long sought ways to understand what drives their resilience and makes them impervious to treatment. Now researchers have uncovered a molecular chain of events that interferes with a key mechanism that regulates cell behavior and controls tumor formation.

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Mars rock-ingredient stew seen as plus for habitability

NASA's Curiosity rover is climbing a layered Martian mountain and finding evidence of how ancient lakes and wet underground environments changed, billions of years ago, creating more diverse chemical environments that affected their favorability for microbial life.

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Researchers find bacterial protein that boosts insulin-producing cells in zebrafish

A newly discovered bacterial protein produced in the zebrafish gut triggers insulin-producing beta cells of the pancreas to multiply during early larval development, say researchers. The research potentially has human health implications. The findings, which could someday lead to new diabetes treatments, highlight the important role of resident microbes in development of the pancreas,

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New technique switches key biomolecules on and off

A new technique that will allow scientists to determine the effects of turning on and off a set of molecules involved in almost every cellular pathway, determine their downstream effects, and uncover new drug targets has been developed by researchers.

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