Led by UCI professor of molecular biology & biochemistry Christopher C.W. Hughes, the research team successfully established multiple vascularized micro-organs on an industry-standard 96-well plate. Hughes and the study’s first author, Duc T. T. Phan, showed that these miniature tissues are much better at reproducing human drug responses than previous model systems. Hughes and his group have shown how the flow of a blood substitute through the vascular network they created can deliver nutrients to multiple kinds of tissues, including heart, pancreas, brain and various tumors.