A closer look at brain organoid development

Researchers already have succeeded in growing so-called ‘cerebral organoids’ in a dish — clusters of cells that self-organize into small brain-like structures. Scientists have now further characterized these organoids. They demonstrate that, like in the human brain, so-called forebrain organizing centers orchestrate developmental processes in the organoid, and that organoids recapitulate the timing of neuronal differentiation events found in human brains.