The job of a protein hub inside the nucleus of a cell is similar to that of a chef in a kitchen. Both need to manage multiple tasks efficiently for a successful outcome. For the chef, if they spend too much time chopping vegetables and neglect the main course cooking on the stove, the result is a burnt dish. Similarly, if the protein hub spends too much time interacting with one protein and is not given a break to accomplish its other important tasks, it can lead to disease states such as cancer.
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Source: Phys.org