Bacteria used as factories to produce cancer drugs

Researchers at the Novo Nordisk Foundation Center for Biosustainability in Denmark have developed a method of producing P450 enzymes used by plants to defend against predators and microbes in bacterial cell factories. The process could facilitate the production of large quantities of the enzymes, which are also involved in the biosynthesis of active ingredients of cancer drugs.

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Scientists design molecular system for artificial photosynthesis

Photosynthesis in green plants converts solar energy to stored chemical energy by transforming atmospheric carbon dioxide and water into sugar molecules that fuel plant growth. Scientists have been trying to artificially replicate this energy conversion process, with the objective of producing environmentally friendly and sustainable fuels, such as hydrogen and methanol. But mimicking key functions of the photosynthetic center, where specialized biomolecules carry out photosynthesis, has proven challenging. Artificial photosynthesis requires designing a molecular system that can absorb light, transport and separate electrical charge, and catalyze fuel-producing reactions—all complicated processes that must operate synchronously to achieve high energy-conversion efficiency.

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Gaining knowledge by simplification

The "strong force" plays a crucial role for the existence of matter in the visible universe. Scientists at TU Darmstadt are carrying out research in that field and recently published their results in Physical Review Letters. To describe the processes in the nucleus they used a method of theoretical simplification which might be applicable to heavier nuclei.

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New approach to antibiotic therapy is a dead end for pathogens

The World Health Organization WHO is currently warning of an antibiotics crisis. The fear is that we are moving into a post-antibiotic era, during which simple bacterial infections would no longer be treatable. According to WHO forecasts, antibiotic-resistant pathogens could become the most frequent cause of unnatural deaths within just a few years. This dramatic threat to public health is due to the rapid evolution of resistance to antibiotics, which continues to reduce the spectrum of effective antibacterial drugs. We urgently need new treatments. In addition to developing new antibiotic drugs, a key strategy is to boost the effectiveness of existing antibiotics by new therapeutic approaches.

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Inlet Acoustic Data from a High Bypass Ratio Turbofan Rotor in an Internal Flow Component Test Facility

Abstract: In February 2017, aerodynamic and acoustic testing was completed on a scale-model high bypass ratio turbofan rotor, R4, in an internal flow component test facility. The objective of testing was to determine the aerodynamic and acoustic impact of fan casing treatments designed to reduce noise. The baseline configuration consisted of the R4 rotor with a hardwall fan case. Data are presented for a baseline acoustic run with fan exit instrumentation removed to give a clean acoustic configuration.

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Researchers investigate decision-making by physical phenomena

(Phys.org)—Decision-making is typically thought of as something done by intelligent living things and, in modern times, computers. But over the past several years, researchers have demonstrated that physical objects such as a metal bar [video], liquids [paper], and lasers can also "make decisions" by responding to feedback from their environments. And they have shown that, in some cases, physical objects can potentially make decisions faster and more accurately than what both humans and computers are capable of.

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Are aliens communicating with neutrino beams?

It is no easy thing to search for signs of intelligent life beyond our solar system. In addition to the incredible distances involved and the fact that we really only have indirect methods at our disposal, there is also the small problem of not knowing exactly what to look for. If intelligent life does exist beyond our solar system, would they even communicate as we do, using radio transmitters and similar forms of technology?

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