{"id":269557,"date":"2017-02-02T15:10:21","date_gmt":"2017-02-02T19:10:21","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2017\/02\/170202141021.htm"},"modified":"2017-02-02T15:10:21","modified_gmt":"2017-02-02T19:10:21","slug":"shedding-light-on-the-brakes-of-akt-activity","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=269557","title":{"rendered":"Shedding light on the brakes of Akt activity"},"content":{"rendered":"<p>Changes leading to the hyperactivation of the protein kinase Akt are observed in almost 50% of all human tumors. Understanding Akt\u2019s regulatory mechanisms is therefore essential for developing and improving cancer therapies. Researchers propose a completely new model of Akt regulation, limiting its activity to discrete locations within the cell \u2013 cellular membranes. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Changes leading to the hyperactivation of the protein kinase Akt are observed in almost 50% of all human tumors. Understanding Akt&rsquo;s regulatory mechanisms is therefore essential for developing and improving cancer therapies. Researchers propose a completely new model of Akt regulation, limiting its activity to discrete locations within the cell &ndash; cellular membranes.<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-269557","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/269557","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=269557"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/269557\/revisions"}],"predecessor-version":[{"id":269558,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/269557\/revisions\/269558"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=269557"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=269557"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=269557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}