{"id":314348,"date":"2017-05-11T08:04:40","date_gmt":"2017-05-11T12:04:40","guid":{"rendered":"https:\/\/ntrs.nasa.gov\/search.jsp?R=20170003838"},"modified":"2017-05-11T08:04:40","modified_gmt":"2017-05-11T12:04:40","slug":"three-dimensional-organotypic-co-culture-model-of-intestinal-epithelial-cells-and-macrophages-to-study-salmonella-enterica-colonization-patterns","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=314348","title":{"rendered":"Three-Dimensional Organotypic Co-Culture Model of Intestinal Epithelial Cells and Macrophages to Study &#8220;Salmonella Enterica&#8221; Colonization Patterns"},"content":{"rendered":"<p>Abstract: Three-dimensional\/3-D organotypic models of human intestinal epithelium mimic the differentiated form and function of parental tissues often not exhibited by 2-D monolayers and respond to Salmonella in ways that reflect in vivo infections. To further enhance the physiological relevance of 3-D models to more closely approximate in vivo intestinal microenvironments during infection, we developed and validated a novel 3-D intestinal co-culture model containing multiple epithelial cell types and &#8230;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abstract: Three-dimensional\/3-D organotypic models of human intestinal epithelium mimic the differentiated form and function of parental tissues often not exhibited by 2-D monolayers and respond to Salmonella in ways that reflect in vivo infections. To&#8230;<\/p>\n","protected":false},"author":60,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-314348","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/314348","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/60"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=314348"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/314348\/revisions"}],"predecessor-version":[{"id":314349,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/314348\/revisions\/314349"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=314348"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=314348"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=314348"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}