{"id":325365,"date":"2017-06-05T11:00:03","date_gmt":"2017-06-05T15:00:03","guid":{"rendered":"http:\/\/spaceweekly.com\/?guid=b0b9263d790f95974cc5ce94c1bc3fc0"},"modified":"2017-06-05T11:00:03","modified_gmt":"2017-06-05T15:00:03","slug":"rna-lifespan-determination-during-transcription","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=325365","title":{"rendered":"RNA lifespan determination during transcription"},"content":{"rendered":"<p>Control of RNA lifespan is vital for the proper functioning of our cells. Marc B\u00fchler&#8217;s group at the Friedrich Miescher Institute for Biomedical Research (FMI) has discovered a novel mechanism determining the fate of RNA in mammalian cells: two proteins involved in RNA interference &#8211; Dgcr8 and Drosha &#8211; together with a methyltransferase, Mettl3, mark nascent RNAs for degradation as they are transcribed. This mechanism allows RNA transcripts to &#8220;remember&#8221; the conditions under which they were synthesized.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Control of RNA lifespan is vital for the proper functioning of our cells. Marc B&uuml;hler&#8217;s group at the Friedrich Miescher Institute for Biomedical Research (FMI) has discovered a novel mechanism determining the fate of RNA in mammalian cells: two proteins involved in RNA interference &#8211; Dgcr8 and Drosha &#8211; together with a methyltransferase, Mettl3, mark nascent RNAs for degradation as they are transcribed. This mechanism allows RNA transcripts to &#8220;remember&#8221; the conditions under which they were synthesized.<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-325365","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/325365","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=325365"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/325365\/revisions"}],"predecessor-version":[{"id":325366,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/325365\/revisions\/325366"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=325365"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=325365"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=325365"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}