{"id":339740,"date":"2017-07-03T17:05:01","date_gmt":"2017-07-03T21:05:01","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2017\/07\/170703170501.htm"},"modified":"2017-07-03T17:05:01","modified_gmt":"2017-07-03T21:05:01","slug":"novel-mechanism-underlying-efficacy-of-common-heart-failure-drug-identified","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=339740","title":{"rendered":"Novel mechanism underlying efficacy of common heart failure drug identified"},"content":{"rendered":"<p>Beta-blocker drugs serve a key role in the treatment of heart failure, preventing bombardment of the heart by catecholamines &#8212; substances like epinephrine and norepinephrine &#8212; which overexcite and stress the heart. But not all HF patients respond to beta-blockers, for reasons that are unclear. Now, researchers show that dysfunction of beta-adrenergic receptor 3 and consequent decreases in a critical cardioprotective phospholipid may be to blame. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Beta-blocker drugs serve a key role in the treatment of heart failure, preventing bombardment of the heart by catecholamines &#8212; substances like epinephrine and norepinephrine &#8212; which overexcite and stress the heart. But not all HF patients respond to &#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-339740","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/339740","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=339740"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/339740\/revisions"}],"predecessor-version":[{"id":339741,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/339740\/revisions\/339741"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=339740"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=339740"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=339740"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}