{"id":373948,"date":"2017-09-15T09:30:03","date_gmt":"2017-09-15T13:30:03","guid":{"rendered":"https:\/\/spaceweekly.com\/?guid=8dc8c95dc84296fc6b6069bf71a2a1a9"},"modified":"2017-09-15T09:30:03","modified_gmt":"2017-09-15T13:30:03","slug":"metal-catalyzed-addition-of-saturated-carbon-into-c-c-bonds-a-relevant-reaction-for-the-synthesis-type-ii-polyketides-2","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=373948","title":{"rendered":"Metal-catalyzed addition of saturated carbon into C-C bonds: A relevant reaction for the synthesis type II polyketides"},"content":{"rendered":"<p>(Phys.org)\u2014Type II polyketides are a class of compounds found in nature as secondary metabolites derived from microorganisms. Their complex structures are characterized by fused polycyclic aromatic rings decorated with a profusion of ketones and hydroxyl groups. Many common antibiotics, anti-fungal, and anti-cancer drugs are type II polyketides or are derivatives of these naturally-occurring compounds. However the &#8220;laboratory synthesis&#8221; of type II polyketides is often challenging; as in living systems, it is a highly selective multi-step enzymatic process.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Phys.org)&mdash;Type II polyketides are a class of compounds found in nature as secondary metabolites derived from microorganisms. Their complex structures are characterized by fused polycyclic aromatic rings decorated with a profusion of ketones and hydroxyl groups. Many common antibiotics, anti-fungal, and anti-cancer drugs are type II polyketides or are derivatives of these naturally-occurring compounds. However the &#8220;laboratory synthesis&#8221; of type II polyketides is often challenging; as in living systems, it is a highly selective multi-step enzymatic process.<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-373948","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/373948","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=373948"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/373948\/revisions"}],"predecessor-version":[{"id":373949,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/373948\/revisions\/373949"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=373948"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=373948"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=373948"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}