{"id":385963,"date":"2017-10-10T14:32:27","date_gmt":"2017-10-10T18:32:27","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2017\/10\/171010143227.htm"},"modified":"2017-10-10T14:32:27","modified_gmt":"2017-10-10T18:32:27","slug":"unexpected-regulation-of-transcription-factors-critical-to-development","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=385963","title":{"rendered":"Unexpected regulation of transcription factors critical to development"},"content":{"rendered":"<p>Developmental biologists have for the first time described how two transcription factors that are &#8216;absolutely essential for human development&#8217; are regulated by a cell surface metalloprotease known as ADAM13. The discovery adds to knowledge of how cells migrate in vertebrate embryos, how stem cells differentiate and how cancer cells metastasize. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Developmental biologists have for the first time described how two transcription factors that are &#8216;absolutely essential for human development&#8217; are regulated by a cell surface metalloprotease known as ADAM13. The discovery adds to knowledge of how cells&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-385963","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/385963","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=385963"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/385963\/revisions"}],"predecessor-version":[{"id":385964,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/385963\/revisions\/385964"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=385963"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=385963"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=385963"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}