{"id":389433,"date":"2017-10-17T06:23:44","date_gmt":"2017-10-17T10:23:44","guid":{"rendered":"http:\/\/spaceweekly.com\/?guid=451ba91a078d0f2d91f2399d84669ff3"},"modified":"2017-10-17T06:23:44","modified_gmt":"2017-10-17T10:23:44","slug":"clues-to-the-innate-drug-resistance-of-a-cocoa-fermenting-pathogen-3","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=389433","title":{"rendered":"Clues to the innate drug resistance of a cocoa-fermenting pathogen"},"content":{"rendered":"<p>At first glance, the yeast Candida krusei seems as innocuous as microbes come: it&#8217;s used for fermenting cocoa beans and gives chocolate its pleasant aroma. But it&#8217;s increasingly found as a pathogen in immunocompromised patients\u2014and C. krusei infections aren&#8217;t always easy to cure. This yeast is naturally resistant to fluconazole, a first-line antifungal that&#8217;s vital not just for treating many fungal infections but also for preventing them in susceptible populations. In the September issue of G3, Cuomo et al. unveil the first whole-genome sequence of a clinical sample of C. krusei, providing leads on genes that may be important for the species&#8217; fluconazole resistance.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>At first glance, the yeast Candida krusei seems as innocuous as microbes come: it&#8217;s used for fermenting cocoa beans and gives chocolate its pleasant aroma. But it&#8217;s increasingly found as a pathogen in immunocompromised patients&mdash;and C. krusei infections aren&#8217;t always easy to cure. This yeast is naturally resistant to fluconazole, a first-line antifungal that&#8217;s vital not just for treating many fungal infections but also for preventing them in susceptible populations. In the September issue of G3, Cuomo et al. unveil the first whole-genome sequence of a clinical sample of C. krusei, providing leads on genes that may be important for the species&#8217; fluconazole resistance.<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-389433","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/389433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=389433"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/389433\/revisions"}],"predecessor-version":[{"id":389434,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/389433\/revisions\/389434"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=389433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=389433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=389433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}