{"id":390649,"date":"2017-10-19T02:28:38","date_gmt":"2017-10-19T06:28:38","guid":{"rendered":"http:\/\/spaceweekly.com\/?guid=01086d941c9cc4daf1f666307ac445df"},"modified":"2017-10-19T02:28:38","modified_gmt":"2017-10-19T06:28:38","slug":"researchers-watch-in-real-time-as-fat-encased-drug-nanoparticles-invade-skin-cells-2","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=390649","title":{"rendered":"Researchers watch in real time as fat-encased drug nanoparticles invade skin cells"},"content":{"rendered":"<p>Some anti-cancer drugs are encapsulated to allow gradual release, spreading their effect over a longer time. For example, one formulation of the chemotherapy doxorubicin (the FDA-approved drug Doxil) encloses molecules of the drug in fatty nano-spheres called liposomes, which allows the drug to circulate longer in the blood. However, the use of liposome &#8220;capsules&#8221; often comes with side-effects. Unfortunately, liposomes often end up in skin cells, resulting in rash and even lesions. These side effects can be &#8220;dose-limiting,&#8221; meaning that the amount of medicine that can be used is limited by the severity of side-effects. If researchers could decrease the side-effects of liposome use, doctors could use higher doses of these drugs, perhaps leading to better cancer control.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some anti-cancer drugs are encapsulated to allow gradual release, spreading their effect over a longer time. For example, one formulation of the chemotherapy doxorubicin (the FDA-approved drug Doxil) encloses molecules of the drug in fatty nano-spheres&#8230;<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-390649","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/390649","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=390649"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/390649\/revisions"}],"predecessor-version":[{"id":390650,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/390649\/revisions\/390650"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=390649"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=390649"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=390649"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}