{"id":393631,"date":"2017-10-24T10:49:16","date_gmt":"2017-10-24T14:49:16","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2017\/10\/171024104916.htm"},"modified":"2017-10-24T10:49:16","modified_gmt":"2017-10-24T14:49:16","slug":"stronger-twist-to-cytotoxic-amyloid-fibrils","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=393631","title":{"rendered":"Stronger twist to cytotoxic amyloid fibrils"},"content":{"rendered":"<p>For the first time, researchers performed a structural comparison of two types of amyloid fibrils that have been associated with Parkinson&#8217;s disease. Using a combination of experimental methods they show that a cytotoxic C-terminal truncated form of the alpha-synuclein protein that is abundant in vivo, aggregates into more strongly twisted fibrils that are more exposed to water. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>For the first time, researchers performed a structural comparison of two types of amyloid fibrils that have been associated with Parkinson&#8217;s disease. Using a combination of experimental methods they show that a cytotoxic C-terminal truncated form of th&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-393631","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/393631","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=393631"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/393631\/revisions"}],"predecessor-version":[{"id":393632,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/393631\/revisions\/393632"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=393631"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=393631"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=393631"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}