{"id":409543,"date":"2017-11-29T09:33:29","date_gmt":"2017-11-29T13:33:29","guid":{"rendered":"https:\/\/spaceweekly.com\/?guid=e493fc93b9b56098ac3702e27d0b4af5"},"modified":"2017-11-29T09:33:29","modified_gmt":"2017-11-29T13:33:29","slug":"the-light-chain-subunits-of-therapeutic-antibodies-impact-drug-performance-and-yield","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=409543","title":{"rendered":"The light chain subunits of therapeutic antibodies impact drug performance and yield"},"content":{"rendered":"<p>Antibody-based drugs have long been a mainstay of treatment for many conditions, especially cancer and autoimmune diseases, but there may still be room for improving these therapies. An A*STAR study has found that changes to a part of the antibodies that&#8217;s often overlooked by protein engineers and drug companies can have dramatic effects on target binding and manufacturing yield.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Antibody-based drugs have long been a mainstay of treatment for many conditions, especially cancer and autoimmune diseases, but there may still be room for improving these therapies. An A*STAR study has found that changes to a part of the antibodies th&#8230;<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-409543","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/409543","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=409543"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/409543\/revisions"}],"predecessor-version":[{"id":409544,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/409543\/revisions\/409544"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=409543"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=409543"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=409543"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}