{"id":415686,"date":"2017-12-11T16:36:55","date_gmt":"2017-12-11T20:36:55","guid":{"rendered":"http:\/\/spaceweekly.com\/?guid=1a7ee23dc779ac1a3588a71fe6a32bf1"},"modified":"2017-12-11T16:36:55","modified_gmt":"2017-12-11T20:36:55","slug":"patients-individual-genomes-may-affect-efficacy-safety-of-gene-editing-4","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=415686","title":{"rendered":"Patients&#8217; individual genomes may affect efficacy, safety of gene editing"},"content":{"rendered":"<p>Gene editing has begun to be tested in clinical trials, using CRISPR-Cas9 and other technologies to directly edit DNA inside people&#8217;s cells, and multiple trials are recruiting or in the planning stages. A new study led by Boston Children&#8217;s Hospital and the University of Montreal raises a note of caution, finding that person-to-person genetic differences may undercut the efficacy of the gene editing process or, in more rare cases, cause a potentially dangerous &#8220;off target&#8221; effect.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gene editing has begun to be tested in clinical trials, using CRISPR-Cas9 and other technologies to directly edit DNA inside people&#8217;s cells, and multiple trials are recruiting or in the planning stages. A new study led by Boston Children&#8217;s Hospital and&#8230;<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-415686","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/415686","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=415686"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/415686\/revisions"}],"predecessor-version":[{"id":415692,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/415686\/revisions\/415692"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=415686"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=415686"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=415686"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}