{"id":429174,"date":"2018-01-18T11:06:03","date_gmt":"2018-01-18T15:06:03","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/01\/180118100603.htm"},"modified":"2018-01-18T11:06:03","modified_gmt":"2018-01-18T15:06:03","slug":"efficacy-of-antibody-targeting-devics-disease-proven-in-new-animal-model","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=429174","title":{"rendered":"Efficacy of antibody targeting Devic&#8217;s disease proven in new animal model"},"content":{"rendered":"<p>Neuromyelitis optica (NMO) is an autoimmune disease associated with NMO immunoglobulin G (NMO-IgG). A cure for NMO remains elusive. Researchers recently established a localized NMO rat model by injecting NMO-IgG into the spinal cord, and assessed the efficacy of anti-repulsive guidance molecule-a (RGMa) antibody in treating NMO. They found anti-RGMa antibody delayed the onset and attenuated the severity of clinical symptoms of NMO, suggesting that humanized anti-RGMa antibody is a potentially valid therapeutic approach for NMO. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neuromyelitis optica (NMO) is an autoimmune disease associated with NMO immunoglobulin G (NMO-IgG). A cure for NMO remains elusive. Researchers recently established a localized NMO rat model by injecting NMO-IgG into the spinal cord, and assessed the e&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-429174","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/429174","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=429174"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/429174\/revisions"}],"predecessor-version":[{"id":429175,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/429174\/revisions\/429175"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=429174"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=429174"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=429174"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}