{"id":433358,"date":"2018-01-26T08:09:38","date_gmt":"2018-01-26T12:09:38","guid":{"rendered":"http:\/\/spaceweekly.com\/?guid=1e08187c5a9a1c6e0e6fc89a05fa205b"},"modified":"2018-01-26T08:09:38","modified_gmt":"2018-01-26T12:09:38","slug":"when-the-guardian-and-the-caretaker-of-the-genome-join-forces-2","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=433358","title":{"rendered":"When the &#8216;guardian&#8217; and the &#8216;caretaker&#8217; of the genome join forces"},"content":{"rendered":"<p>Biologists and chemists at the University of Konstanz have deciphered a molecular cellular mechanism related to the development of cancer. They report the interaction between the tumour-suppressor protein p53, known as the &#8220;guardian of the genome,&#8221; and the enzyme PARP-1, the &#8220;caretaker of the genome.&#8221; The collaboration with the University of Ulm and the Karlsruhe Institute of Technology (KIT) resulted in an article published in Nucleic Acids Research.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biologists and chemists at the University of Konstanz have deciphered a molecular cellular mechanism related to the development of cancer. They report the interaction between the tumour-suppressor protein p53, known as the &#8220;guardian of the genome,&#8221; and&#8230;<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-433358","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/433358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=433358"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/433358\/revisions"}],"predecessor-version":[{"id":433359,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/433358\/revisions\/433359"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=433358"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=433358"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=433358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}