{"id":435806,"date":"2018-02-05T10:29:18","date_gmt":"2018-02-05T14:29:18","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/02\/180205092918.htm"},"modified":"2018-02-05T10:29:18","modified_gmt":"2018-02-05T14:29:18","slug":"new-genome-editing-method-cuts-back-on-unwanted-genetic-mutations-2","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=435806","title":{"rendered":"New genome-editing method &#8216;cuts back&#8217; on unwanted genetic mutations"},"content":{"rendered":"<p>Gene therapy can potentially correct genetic disorders by directly editing defective genes. CRISPR-Cas9 is a popular gene-editing technology whose clinical utility is limited by its tendency to produce unintended genetic errors. Researchers centered at Osaka University developed a modified CRISPR-Cas9 system that uses single-stranded nicking, rather than DNA cleavage, to generate highly precise changes to a target gene. The technique offers a more accurate and safer editing strategy for future gene therapy applications. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gene therapy can potentially correct genetic disorders by directly editing defective genes. CRISPR-Cas9 is a popular gene-editing technology whose clinical utility is limited by its tendency to produce unintended genetic errors. Researchers centered at&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-435806","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/435806","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=435806"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/435806\/revisions"}],"predecessor-version":[{"id":435807,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/435806\/revisions\/435807"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=435806"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=435806"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=435806"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}