{"id":444145,"date":"2018-02-22T13:57:22","date_gmt":"2018-02-22T17:57:22","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/02\/180222125722.htm"},"modified":"2018-02-22T13:57:22","modified_gmt":"2018-02-22T17:57:22","slug":"cancer-risk-associated-with-key-epigenetic-changes-occurring-through-normal-aging-process","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=444145","title":{"rendered":"Cancer risk associated with key epigenetic changes occurring through normal aging process"},"content":{"rendered":"<p>Some scientists have hypothesized that tumor-promoting changes in cells during cancer development &#8212; particularly an epigenetic change involving DNA methylation &#8212; arise from rogue cells escaping a natural cell deterioration process called senescence. Now, researchers have demonstrated that instead, tumor-associated epigenetic states evolve erratically during early stages of tumor development, eventually selecting for a subset of genes that undergo the most changes during normal aging and in early tumor development. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some scientists have hypothesized that tumor-promoting changes in cells during cancer development &#8212; particularly an epigenetic change involving DNA methylation &#8212; arise from rogue cells escaping a natural cell deterioration process called senescence. &#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-444145","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/444145","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=444145"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/444145\/revisions"}],"predecessor-version":[{"id":444146,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/444145\/revisions\/444146"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=444145"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=444145"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=444145"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}