{"id":468133,"date":"2018-04-26T10:28:47","date_gmt":"2018-04-26T14:28:47","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/04\/180426102847.htm"},"modified":"2018-04-26T10:28:47","modified_gmt":"2018-04-26T14:28:47","slug":"accepted-or-rejected-uncovering-how-fate-of-b-cell-is-determined","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=468133","title":{"rendered":"Accepted or rejected? Uncovering how fate of B cell is determined"},"content":{"rendered":"<p>Researchers identify the plasma cell-prone B cells in the light zone of germinal centers. Higher expression of the proteins ICAM-1 and SLAM in those cells facilitates more stable contacts with Tfh cells, suggesting that strength of Tfh-GC B cell interaction critically regulates formation of plasma cell precursors. The findings serve as important information for the development of effective vaccines against viral infection. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers identify the plasma cell-prone B cells in the light zone of germinal centers. Higher expression of the proteins ICAM-1 and SLAM in those cells facilitates more stable contacts with Tfh cells, suggesting that strength of Tfh-GC B cell intera&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-468133","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/468133","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=468133"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/468133\/revisions"}],"predecessor-version":[{"id":468134,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/468133\/revisions\/468134"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=468133"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=468133"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=468133"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}