{"id":468190,"date":"2018-04-26T12:59:37","date_gmt":"2018-04-26T16:59:37","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/04\/180426125937.htm"},"modified":"2018-04-26T12:59:37","modified_gmt":"2018-04-26T16:59:37","slug":"crisprcas9-silences-gene-associated-with-high-cholesterol","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=468190","title":{"rendered":"CRISPR\/Cas9 silences gene associated with high cholesterol"},"content":{"rendered":"<p>Biomedical engineers have used a CRISPR\/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment. This marks the first time researchers have delivered CRISPR\/Cas9 repressors for targeted therapeutic gene silencing in adult animal models. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biomedical engineers have used a CRISPR\/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatme&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-468190","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/468190","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=468190"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/468190\/revisions"}],"predecessor-version":[{"id":468191,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/468190\/revisions\/468191"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=468190"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=468190"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=468190"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}