{"id":476078,"date":"2018-05-16T14:46:24","date_gmt":"2018-05-16T18:46:24","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/05\/180516144624.htm"},"modified":"2018-05-16T14:46:24","modified_gmt":"2018-05-16T18:46:24","slug":"novel-therapy-inhibits-complement-to-preserve-neurons-and-reduce-inflammation-after-stroke","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=476078","title":{"rendered":"Novel therapy inhibits complement to preserve neurons and reduce inflammation after stroke"},"content":{"rendered":"<p>Researchers report that, after ischemic stroke, the complement system identifies stressed but salvageable neurons for removal by microglial phagocytosis. To preserve these neurons, the investigators designed a novel therapeutic that targets a complement inhibitor to a damage signal expressed after stroke. A single post-stroke injection protected neurons from microglial attack in a preclinical model, reducing neuronal loss. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers report that, after ischemic stroke, the complement system identifies stressed but salvageable neurons for removal by microglial phagocytosis. To preserve these neurons, the investigators designed a novel therapeutic that targets a complemen&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-476078","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/476078","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=476078"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/476078\/revisions"}],"predecessor-version":[{"id":476079,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/476078\/revisions\/476079"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=476078"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=476078"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=476078"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}