{"id":481567,"date":"2018-06-01T09:38:02","date_gmt":"2018-06-01T13:38:02","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/06\/180601093802.htm"},"modified":"2018-06-01T09:38:02","modified_gmt":"2018-06-01T13:38:02","slug":"structure-of-protein-pair-provides-blueprint-for-future-drugs","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=481567","title":{"rendered":"Structure of protein pair provides blueprint for future drugs"},"content":{"rendered":"<p>Researchers have visualized for the first time how the protein SOCS1 &#8216;switches off&#8217; cell signalling to dampen immune responses and block cancer growth. The atomic-level structure of SOCS1 binding to its partner protein JAK could guide the development of drugs that alter disease-causing cell signalling pathways, and may have applications for treating some blood cancers, including leukaemias. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have visualized for the first time how the protein SOCS1 &#8216;switches off&#8217; cell signalling to dampen immune responses and block cancer growth. The atomic-level structure of SOCS1 binding to its partner protein JAK could guide the development o&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-481567","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/481567","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=481567"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/481567\/revisions"}],"predecessor-version":[{"id":481568,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/481567\/revisions\/481568"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=481567"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=481567"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=481567"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}