{"id":495708,"date":"2018-07-10T10:17:04","date_gmt":"2018-07-10T14:17:04","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/07\/180710101704.htm"},"modified":"2018-07-10T10:17:04","modified_gmt":"2018-07-10T14:17:04","slug":"a-chaperonin-protein-groel-has-a-more-complex-mechanism-than-was-thought-before","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=495708","title":{"rendered":"A chaperonin protein, GroEL, has a more complex mechanism than was thought before"},"content":{"rendered":"<p>Scientists have studied molecular interactions in the chaperonin protein GroEL. GroEL is alternately bound and unbound by a co-chaperonin, GroES. Against expectations, the &#8216;football&#8217; complex &#8212; where two GroES units cap the cylindrical GroEL at either end &#8212; was roughly as prevalent as the single-bound &#8216;bullet&#8217; complex. This implies that negative allosteric interactions preventing double-binding of GroEL sometimes fail, and the double-bound complex plays an active role in protein folding. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists have studied molecular interactions in the chaperonin protein GroEL. GroEL is alternately bound and unbound by a co-chaperonin, GroES. Against expectations, the &#8216;football&#8217; complex &#8212; where two GroES units cap the cylindrical GroEL at either &#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-495708","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/495708","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=495708"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/495708\/revisions"}],"predecessor-version":[{"id":495709,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/495708\/revisions\/495709"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=495708"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=495708"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=495708"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}