{"id":504299,"date":"2018-08-03T07:00:04","date_gmt":"2018-08-03T11:00:04","guid":{"rendered":"http:\/\/spaceweekly.com\/?guid=4e12b871a3735bbae8be778502934ab4"},"modified":"2018-08-03T07:00:04","modified_gmt":"2018-08-03T11:00:04","slug":"synthesis-of-the-veterinary-antibiotic-florfenicol-by-a-fast-chemo-enzymatic-route","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=504299","title":{"rendered":"Synthesis of the veterinary antibiotic florfenicol by a fast chemo-enzymatic route"},"content":{"rendered":"<p>Fluorinated structures make up more than 20 percent of modern drugs, but benign and fast fluorination schemes are scarce. In a study published in the European Journal of Organic Chemistry, scientists have now combined dynamic kinetic resolution and nucleophilic fluorination for the asymmetric synthesis of florfenicol, a veterinary antibiotic. After enzymatic resolution of the racemate, two different fluorination strategies both proved effective and fast. One is especially interesting for industrial production.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Fluorinated structures make up more than 20 percent of modern drugs, but benign and fast fluorination schemes are scarce. In a study published in the European Journal of Organic Chemistry, scientists have now combined dynamic kinetic resolution and nuc&#8230;<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-504299","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/504299","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=504299"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/504299\/revisions"}],"predecessor-version":[{"id":504300,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/504299\/revisions\/504300"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=504299"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=504299"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=504299"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}