{"id":508223,"date":"2018-08-13T11:33:12","date_gmt":"2018-08-13T15:33:12","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/08\/180813113312.htm"},"modified":"2018-08-13T11:33:12","modified_gmt":"2018-08-13T15:33:12","slug":"undruggable-cancers-slowed-by-targeting-growth-signals","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=508223","title":{"rendered":"&#8216;Undruggable&#8217; cancers slowed by targeting growth signals"},"content":{"rendered":"<p>As many as 50 percent of human cancer cases &#8212; across a wide variety of tissues &#8212; involve defects in a common cellular growth signaling pathway. These defects have so far defied most attempts to develop targeted therapies. Now researchers have identified a new strategy for potentially treating intractable cancers by decoupling the entire RAS\/MAP Kinase (MAPK) signaling pathway from external growth signals. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>As many as 50 percent of human cancer cases &#8212; across a wide variety of tissues &#8212; involve defects in a common cellular growth signaling pathway. These defects have so far defied most attempts to develop targeted therapies. Now researchers have identif&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-508223","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/508223","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=508223"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/508223\/revisions"}],"predecessor-version":[{"id":508224,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/508223\/revisions\/508224"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=508223"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=508223"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=508223"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}