{"id":522280,"date":"2018-09-17T08:31:01","date_gmt":"2018-09-17T12:31:01","guid":{"rendered":"http:\/\/spaceweekly.com\/?guid=4d23f3bfe6ba5660e29e8ae6e33c7e49"},"modified":"2018-09-17T08:31:01","modified_gmt":"2018-09-17T12:31:01","slug":"proteins-surf-to-mitochondria-a-novel-transport-pathway-discovered","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=522280","title":{"rendered":"Proteins surf to mitochondria \u2013 a novel transport pathway discovered"},"content":{"rendered":"<p>Prof. Johannes Herrmann, a researcher at the Technische Universit\u00e4t Kaiserslautern, Germany, and his team discovered a novel mechanism by which newly synthesized proteins reach their respective target compartment in the cell. Proteins destined to mitochondria, the cell&#8217;s powerhouse, are not directly transported to mitochondria but are directed to the surface of the endoplasmic reticulum, where they &#8220;surf&#8221; along its surface. As shown in Science, this so far unknown mechanism keeps newly synthesized protein transport-competent and might prevent their aggregation. Protein aggregation can be a critical problem leading to human pathologies such as Alzheimer&#8217;s or Parkinson&#8217;s disease.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prof. Johannes Herrmann, a researcher at the Technische Universit&auml;t Kaiserslautern, Germany, and his team discovered a novel mechanism by which newly synthesized proteins reach their respective target compartment in the cell. Proteins destined to mitochondria, the cell&#8217;s powerhouse, are not directly transported to mitochondria but are directed to the surface of the endoplasmic reticulum, where they &#8220;surf&#8221; along its surface. As shown in Science, this so far unknown mechanism keeps newly synthesized protein transport-competent and might prevent their aggregation. Protein aggregation can be a critical problem leading to human pathologies such as Alzheimer&#8217;s or Parkinson&#8217;s disease.<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-522280","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/522280","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=522280"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/522280\/revisions"}],"predecessor-version":[{"id":522281,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/522280\/revisions\/522281"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=522280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=522280"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=522280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}