{"id":528284,"date":"2018-10-01T07:27:24","date_gmt":"2018-10-01T11:27:24","guid":{"rendered":"http:\/\/spaceweekly.com\/?guid=4e793abfe6ec1ce2e30f17ad0d1eaee5"},"modified":"2018-10-01T07:27:24","modified_gmt":"2018-10-01T11:27:24","slug":"unveiling-the-mechanism-protecting-replicated-dna-from-degradation-2","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=528284","title":{"rendered":"Unveiling the mechanism protecting replicated DNA from degradation"},"content":{"rendered":"<p>Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system. They have gained unprecedented access to the underlying mechanism and determined that during DNA replication and cell proliferation in vertebrate cells, AND-1 has two different functions mediated by different domains of AND-1.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system. They&#8230;<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-528284","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/528284","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=528284"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/528284\/revisions"}],"predecessor-version":[{"id":528285,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/528284\/revisions\/528285"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=528284"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=528284"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=528284"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}