{"id":539993,"date":"2018-10-26T10:26:11","date_gmt":"2018-10-26T14:26:11","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/10\/181026102611.htm"},"modified":"2018-10-26T10:26:11","modified_gmt":"2018-10-26T14:26:11","slug":"bioactive-novel-compounds-from-endangered-tropical-plant-species","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=539993","title":{"rendered":"Bioactive novel compounds from endangered tropical plant species"},"content":{"rendered":"<p>Biologists have isolated 17 secondary metabolites, including three novel compounds from the valuable endangered tropical plant species Alangium longiflorum. A newly isolated compound, 8-hydroxytubulosine, showed growth inhibitory effects at submicromolar levels against several human tumor cell lines except for drug transporter-overexpressing cells. Compound 1 caused accumulation of sub-G1 cells with no effect on cell cycle progression, suggesting that this substance is an apoptosis inducer. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biologists have isolated 17 secondary metabolites, including three novel compounds from the valuable endangered tropical plant species Alangium longiflorum. A newly isolated compound, 8-hydroxytubulosine, showed growth inhibitory effects at submicromol&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-539993","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/539993","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=539993"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/539993\/revisions"}],"predecessor-version":[{"id":539994,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/539993\/revisions\/539994"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=539993"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=539993"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=539993"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}