{"id":550010,"date":"2018-11-23T14:51:26","date_gmt":"2018-11-23T18:51:26","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2018\/11\/181123135126.htm"},"modified":"2018-11-23T14:51:26","modified_gmt":"2018-11-23T18:51:26","slug":"never-before-seen-dna-recombination-in-the-brain-linked-to-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=550010","title":{"rendered":"Never-before-seen DNA recombination in the brain linked to Alzheimer&#8217;s disease"},"content":{"rendered":"<p>Scientists have identified gene recombination in neurons that produces thousands of new gene variants within Alzheimer&#8217;s disease brains. The study reveals for the first time how the Alzheimer&#8217;s-linked gene, APP, is recombined by using the same type of enzyme found in HIV. The findings provide rationale for evaluating HIV antiretroviral therapies in people with Alzheimer&#8217;s. It also provides an explanation for why clinical trials for Alzheimer&#8217;s have failed to date. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists have identified gene recombination in neurons that produces thousands of new gene variants within Alzheimer&#8217;s disease brains. The study reveals for the first time how the Alzheimer&#8217;s-linked gene, APP, is recombined by using the same type of &#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-550010","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/550010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=550010"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/550010\/revisions"}],"predecessor-version":[{"id":550011,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/550010\/revisions\/550011"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=550010"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=550010"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=550010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}