{"id":562658,"date":"2018-12-24T11:54:03","date_gmt":"2018-12-24T15:54:03","guid":{"rendered":"https:\/\/ntrs.nasa.gov\/search.jsp?R=20180008605"},"modified":"2018-12-24T11:54:03","modified_gmt":"2018-12-24T15:54:03","slug":"renin-angiotensin-system-ras-in-hematopoietic-stemprogenitor-cells-hspc-predicts-vaso-reparative-dysfunction-and-progression-of-diabetic-retinopathy-dr","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=562658","title":{"rendered":"Renin-Angiotensin System (RAS) in Hematopoietic Stem\/Progenitor Cells (HS\/PC) Predicts Vaso-Reparative Dysfunction and Progression of Diabetic Retinopathy (DR)"},"content":{"rendered":"<p>Abstract: Purpose: We tested the hypothesis that loss of angiotensin converting enzyme 2 (ACE2) within diabetic HS\/PCs (Hematopoietic Stem\/Progenitor Cells) would be detrimental to HS\/PC reparative function, and alter their ability to contribute to vascular remodeling in human subjects and rodent models of DR (Diabetic Retinopathy). Methods: Subjects (n52) were recruited as controls (n13) or diabetics (n39) with either no DR, mild non-proliferative DR (NPDR), moderate NPDR, severe NPDR or proliferative&#8230;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abstract: Purpose: We tested the hypothesis that loss of angiotensin converting enzyme 2 (ACE2) within diabetic HS\/PCs (Hematopoietic Stem\/Progenitor Cells) would be detrimental to HS\/PC reparative function, and alter their ability to contribute to vas&#8230;<\/p>\n","protected":false},"author":60,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-562658","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/562658","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/60"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=562658"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/562658\/revisions"}],"predecessor-version":[{"id":562659,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/562658\/revisions\/562659"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=562658"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=562658"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=562658"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}