{"id":563799,"date":"2019-01-04T09:18:38","date_gmt":"2019-01-04T13:18:38","guid":{"rendered":"https:\/\/spaceweekly.com\/?guid=b09083a936f80faf8527164b82e08c40"},"modified":"2019-01-04T09:18:38","modified_gmt":"2019-01-04T13:18:38","slug":"the-prickle1-gene-regulates-the-differentiation-of-frontal-bone-osteoblasts-in-a-new-animal-model","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=563799","title":{"rendered":"The Prickle1 gene regulates the differentiation of frontal bone osteoblasts in a new animal model"},"content":{"rendered":"<p>A mechanically compromised skull can result from enlarged fontanelles and smaller frontal bones due to defective migration and differentiation of osteoblasts in the skull primordia (developing skull). The Wnt\/Planar cell polarity signaling pathway (Wnt\/PCP), usually regulates cell migration and movement in tissues during embryonic development. In a recent study, conducted by Yong Wan and colleagues at the Center for Craniofacial Regeneration, the central research emphasis was on the Prickle1 gene, a core component of the Wnt\/PCP pathway, in the skull.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A mechanically compromised skull can result from enlarged fontanelles and smaller frontal bones due to defective migration and differentiation of osteoblasts in the skull primordia (developing skull). The Wnt\/Planar cell polarity signaling pathway (Wnt&#8230;<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-563799","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/563799","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=563799"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/563799\/revisions"}],"predecessor-version":[{"id":563800,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/563799\/revisions\/563800"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=563799"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=563799"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=563799"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}