{"id":566300,"date":"2019-01-10T15:17:55","date_gmt":"2019-01-10T19:17:55","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2019\/01\/190110141755.htm"},"modified":"2019-01-10T15:17:55","modified_gmt":"2019-01-10T19:17:55","slug":"decades-old-question-about-protein-found-in-alzheimers-brain-plaques","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=566300","title":{"rendered":"Decades-old question about protein found in Alzheimer&#8217;s brain plaques"},"content":{"rendered":"<p>Alzheimer&#8217;s-affected brains are riddled with so-called amyloid plaques: protein aggregates consisting mainly of amyloid-beta. However, this amyloid-beta is a fragment produced from a precursor protein whose normal function has remained enigmatic for decades. A team of scientists has now uncovered that this amyloid precursor protein modulates neuronal signal transmission through binding to a specific receptor. Modulating this receptor could potentially help treat Alzheimer&#8217;s or other brain diseases. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Alzheimer&#8217;s-affected brains are riddled with so-called amyloid plaques: protein aggregates consisting mainly of amyloid-beta. However, this amyloid-beta is a fragment produced from a precursor protein whose normal function has remained enigmatic for de&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-566300","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/566300","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=566300"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/566300\/revisions"}],"predecessor-version":[{"id":566301,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/566300\/revisions\/566301"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=566300"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=566300"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=566300"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}