{"id":573986,"date":"2019-01-31T12:38:43","date_gmt":"2019-01-31T16:38:43","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2019\/01\/190131113843.htm"},"modified":"2019-01-31T12:38:43","modified_gmt":"2019-01-31T16:38:43","slug":"researchers-breathe-new-life-into-copd-research-using-mouse-models","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=573986","title":{"rendered":"Researchers breathe new life into COPD research using mouse models"},"content":{"rendered":"<p>Researchers revealed that the immune cells basophils caused emphysema in mice with COPD-like features induced by intranasal administration of elastase. They showed that basophils, previously linked mainly to allergies and fighting parasites, initiated a cascade of reactions eventually leading to the release of excess MMP-12 and the destruction of alveolar walls. The team hopes that the findings will lead to breakthroughs in the treatment of COPD. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers revealed that the immune cells basophils caused emphysema in mice with COPD-like features induced by intranasal administration of elastase. They showed that basophils, previously linked mainly to allergies and fighting parasites, initiated &#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-573986","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/573986","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=573986"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/573986\/revisions"}],"predecessor-version":[{"id":573987,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/573986\/revisions\/573987"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=573986"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=573986"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=573986"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}