{"id":586434,"date":"2019-03-01T17:09:23","date_gmt":"2019-03-01T21:09:23","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2019\/03\/190301160923.htm"},"modified":"2019-03-01T17:09:23","modified_gmt":"2019-03-01T21:09:23","slug":"high-fat-diet-and-age-alter-microflora-and-cause-inflammation-in-heart-failure","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=586434","title":{"rendered":"High-fat diet and age alter microflora and cause inflammation in heart failure"},"content":{"rendered":"<p>Growing older and a high-fat diet enriched with omega 6 fatty acids are major contributors to health risks ranging from diabetes to heart failure. How these factors regulate the immune response is now described &#8212; a calorie-dense, obesity-generating diet in aging mice disrupts the composition of the gut microbiome. This correlates with development of a system-wide nonresolving inflammation in acute heart failure, with a notable disruption of the immune cell profile, primarily the neutrophil-leukocyte ratio. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Growing older and a high-fat diet enriched with omega 6 fatty acids are major contributors to health risks ranging from diabetes to heart failure. How these factors regulate the immune response is now described &#8212; a calorie-dense, obesity-generating di&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-586434","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/586434","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=586434"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/586434\/revisions"}],"predecessor-version":[{"id":586435,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/586434\/revisions\/586435"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=586434"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=586434"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=586434"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}