{"id":588002,"date":"2019-03-06T11:06:04","date_gmt":"2019-03-06T15:06:04","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2019\/03\/190306100604.htm"},"modified":"2019-03-06T11:06:04","modified_gmt":"2019-03-06T15:06:04","slug":"anti-inflammatory-drug-is-the-key-to-boosting-cardiac-reprogramming","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=588002","title":{"rendered":"Anti-inflammatory drug is the key to boosting cardiac reprogramming"},"content":{"rendered":"<p>Researchers have developed a high-throughput screening system to identify the NSAID diclofenac as a factor responsible for enhancing cardiac reprogramming in postnatal and adult fibroblasts. Diclofenac functioned during early-stage reprogramming by silencing the cellular signature associated with fibroblasts and inhibiting COX-2 and other molecules associated with inflammation. Ant-inflammation could therefore be used to improve cardiac reprogramming associated with aging. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have developed a high-throughput screening system to identify the NSAID diclofenac as a factor responsible for enhancing cardiac reprogramming in postnatal and adult fibroblasts. Diclofenac functioned during early-stage reprogramming by sil&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-588002","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/588002","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=588002"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/588002\/revisions"}],"predecessor-version":[{"id":588003,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/588002\/revisions\/588003"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=588002"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=588002"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=588002"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}