{"id":588638,"date":"2019-03-07T15:10:36","date_gmt":"2019-03-07T19:10:36","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2019\/03\/190307141036.htm"},"modified":"2019-03-07T15:10:36","modified_gmt":"2019-03-07T19:10:36","slug":"crystal-clear-view-of-a-key-neuronal-receptor-opens-door-for-new-targeted-drugs-2","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=588638","title":{"rendered":"Crystal-clear view of a key neuronal receptor opens door for new, targeted drugs"},"content":{"rendered":"<p>One of the most important protein signaling systems that controls neuronal guidance consists of the cell surface receptor &#8216;Robo&#8217; and its cognate external guidance cue &#8216;Slit.&#8217; The deficit of either of these proteins results in defects in brain structure and function. Researchers have now discovered the intricate molecular mechanism that allows the guidance receptor &#8216;Robo&#8217; to react to signals in its environment, while avoiding premature activity that can lead to harmful outcomes. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>One of the most important protein signaling systems that controls neuronal guidance consists of the cell surface receptor &#8216;Robo&#8217; and its cognate external guidance cue &#8216;Slit.&#8217; The deficit of either of these proteins results in defects in brain structure&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-588638","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/588638","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=588638"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/588638\/revisions"}],"predecessor-version":[{"id":588639,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/588638\/revisions\/588639"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=588638"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=588638"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=588638"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}