{"id":598342,"date":"2019-03-27T11:26:52","date_gmt":"2019-03-27T15:26:52","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2019\/03\/190327112652.htm"},"modified":"2019-03-27T11:26:52","modified_gmt":"2019-03-27T15:26:52","slug":"how-nerve-cells-control-misfolded-proteins","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=598342","title":{"rendered":"How nerve cells control misfolded proteins"},"content":{"rendered":"<p>Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal. They have identified the so-called Linear Ubiquitin Chain Assembly Complex, Lubac for short, as a crucial player in controlling misfolded proteins in cells. The group is hoping to find a new therapeutic approach to treat neurodegenerative diseases such as Alzheimer&#8217;s, Parkinson&#8217;s or Huntington&#8217;s chorea, all of which are associated with misfolded proteins. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have identified a protein complex that marks misfolded proteins, stops them from interacting with other proteins in the cell and directs them towards disposal. They have identified the so-called Linear Ubiquitin Chain Assembly Complex, Luba&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-598342","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/598342","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=598342"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/598342\/revisions"}],"predecessor-version":[{"id":598343,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/598342\/revisions\/598343"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=598342"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=598342"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=598342"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}