{"id":599613,"date":"2019-04-01T05:00:08","date_gmt":"2019-04-01T09:00:08","guid":{"rendered":"http:\/\/spaceweekly.com\/?guid=5bc412b918084d63aad9f9508cfc3409"},"modified":"2019-04-01T05:00:08","modified_gmt":"2019-04-01T09:00:08","slug":"depression-obesity-chronic-pain-could-be-treated-by-targeting-the-same-key-protein","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=599613","title":{"rendered":"Depression, obesity, chronic pain could be treated by targeting the same key protein"},"content":{"rendered":"<p>Major depression, obesity and chronic pain are all linked to the effects of one protein, called &#8220;FK506-binding protein 51,&#8221; or FKBP51. Until now, efforts to inhibit this target have been hampered by the difficulty of finding something specific enough to do the job and not affect similar proteins. Now a research group has developed a highly selective compound that can effectively block FKBP51 in mice, relieving chronic pain and having positive effects on diet-induced obesity and mood. The new compound also could have applications in alcoholism and brain cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Major depression, obesity and chronic pain are all linked to the effects of one protein, called &#8220;FK506-binding protein 51,&#8221; or FKBP51. Until now, efforts to inhibit this target have been hampered by the difficulty of finding something specific enough t&#8230;<\/p>\n","protected":false},"author":0,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-599613","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/599613","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=599613"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/599613\/revisions"}],"predecessor-version":[{"id":599614,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/599613\/revisions\/599614"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=599613"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=599613"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=599613"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}