{"id":605758,"date":"2019-04-11T14:51:52","date_gmt":"2019-04-11T18:51:52","guid":{"rendered":"https:\/\/www.sciencedaily.com\/releases\/2019\/04\/190411145152.htm"},"modified":"2019-04-11T14:51:52","modified_gmt":"2019-04-11T18:51:52","slug":"broken-mitochondria-use-eat-me-proteins-to-summon-their-executioners-3","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=605758","title":{"rendered":"Broken mitochondria use &#8216;eat me&#8217; proteins to summon their executioners"},"content":{"rendered":"<p>When mitochondria become damaged, they avoid causing further problems by signaling cellular proteins to degrade them. In a new study, scientists report that they have discovered how the cells trigger this process, which is called mitophagy. In cells with broken mitochondria, two proteins &#8212; NIPSNAP 1 and NIPSNAP 2 &#8212; accumulate on the mitochondrial surface, functioning as &#8216;eat me&#8217; signals, recruiting the cellular machinery that will destroy them. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>When mitochondria become damaged, they avoid causing further problems by signaling cellular proteins to degrade them. In a new study, scientists report that they have discovered how the cells trigger this process, which is called mitophagy. In cells wi&#8230;<\/p>\n","protected":false},"author":61,"featured_media":615444,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-605758","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/605758","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/61"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=605758"}],"version-history":[{"count":1,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/605758\/revisions"}],"predecessor-version":[{"id":605759,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/605758\/revisions\/605759"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=605758"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=605758"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=605758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}