{"id":623262,"date":"2019-07-09T12:50:02","date_gmt":"2019-07-09T16:50:02","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=623262"},"modified":"2019-07-09T12:50:02","modified_gmt":"2019-07-09T16:50:02","slug":"small-volume-high-throughput-organic-synthesis","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=623262","title":{"rendered":"Small-volume, high-throughput organic synthesis"},"content":{"rendered":"<p>University of Groningen Professor of Drug Design, Alexander D\u00f6mling, has devised a method to rapidly synthesize thousands of new molecules and evaluate their properties as potential drugs. In a paper published by Science Advances on 5 July, he shows that this method works well when applied to boronic acid chemistry, an important technique in synthetic organic chemistry. The study also produced an inhibitor of the phosphatase MptpB, a virulence factor of Mycobacterium tuberculosis, which had previously been considered an &#8216;undruggable&#8217; target.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/phys.org\/news\/2019-07-small-volume-high-throughput-synthesis.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Small-volume, high-throughput organic synthesis<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: Phys.org&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>University of Groningen Professor of Drug Design, Alexander D\u00f6mling, has devised a method to rapidly synthesize thousands of new molecules and evaluate their properties as potential drugs. In a paper&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-623262","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-phys-org"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/623262","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=623262"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/623262\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=623262"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=623262"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=623262"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}