{"id":630959,"date":"2019-09-17T06:56:50","date_gmt":"2019-09-17T10:56:50","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=630959"},"modified":"2019-09-17T06:56:50","modified_gmt":"2019-09-17T10:56:50","slug":"bioengineering-organ-specific-tissues-with-high-cellular-density-and-embedded-vascular-channels","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=630959","title":{"rendered":"Bioengineering organ-specific tissues with high cellular density and embedded vascular channels"},"content":{"rendered":"<p>Bioengineers study the development of organ-specific tissues in the lab for therapeutic applications. However, the process is highly challenging, since it requires the fabrication and maintenance of dense cellular constructs composed of approximately 108 cell\/mL. Research teams have used organ building blocks (OBBs) composed of patient-specific-induced pluripotent stem cell (iPSC)-derived organoids as a pathway to achieve the requisite cell density, microarchitecture and tissue function. However, OBBs hitherto remain to be assembled into 3-D tissue constructs. In a recent report, Mark A. Skylar-Scott and an interdisciplinary research team at the Wyss Institute for Biologically Inspired Engineering and the John A. Paulson School of Engineering and Applied Sciences at Harvard University, developed a new biomanufacturing method.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/phys.org\/news\/2019-09-bioengineering-organ-specific-tissues-high-cellular.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Bioengineering organ-specific tissues with high cellular density and embedded vascular channels<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: Phys.org&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bioengineers study the development of organ-specific tissues in the lab for therapeutic applications. However, the process is highly challenging, since it requires the fabrication and maintenance of dense cellular constructs&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-630959","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-phys-org"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/630959","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=630959"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/630959\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=630959"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=630959"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=630959"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}