{"id":645078,"date":"2020-02-03T11:12:50","date_gmt":"2020-02-03T15:12:50","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=645078"},"modified":"2020-02-03T11:12:50","modified_gmt":"2020-02-03T15:12:50","slug":"chemists-propose-new-approach-to-the-synthesis-of-abcd-ring-system-of-alpkinidine","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=645078","title":{"rendered":"Chemists propose new approach to the synthesis of ABCD ring system of alpkinidine"},"content":{"rendered":"<p>RUDN University chemists, together with Indian colleagues from Goa University, have synthesized an analog of alkaloid of alpkinidine, a substance with a signified cytotoxic effect. Before the team&#8217;s research, there was no convenient way to synthesize such heterocycles. The authors were able to obtain an analog of alpkinidine using the Negishi reaction as a key stage (a palladium-catalyzed combination of aryl halides with organozincs) followed by annelation (completion) of an additional cycle to the resulting heterocyclic framework. The method could potentially become the basis for a scheme of the synthesis of alpkinidine. The article is published in ChemistrySelect.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/phys.org\/news\/2020-02-chemists-approach-synthesis-abcd-alpkinidine.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Chemists propose new approach to the synthesis of ABCD ring system of alpkinidine<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: Phys.org&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>RUDN University chemists, together with Indian colleagues from Goa University, have synthesized an analog of alkaloid of alpkinidine, a substance with a signified cytotoxic effect. Before the team&#8217;s research, there&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-645078","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-phys-org"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/645078","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=645078"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/645078\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=645078"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=645078"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=645078"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}