{"id":648364,"date":"2020-03-05T10:50:02","date_gmt":"2020-03-05T14:50:02","guid":{"rendered":"https:\/\/spaceweekly.com\/?p=648364"},"modified":"2020-03-05T10:50:02","modified_gmt":"2020-03-05T14:50:02","slug":"research-structural-and-functional-studies-of-corticotropin-releasing-factor-receptors","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=648364","title":{"rendered":"Research: Structural and functional studies of corticotropin-releasing factor receptors"},"content":{"rendered":"<p>CRF1R and CRF2R, two members of class B G-protein-coupled receptors (GPCRs), are widely expressed in the central and peripheral nervous systems and activated by the corticoliberin family of peptide hormones that include CRF and urocortins 1-3 (UCN1-UCN3). The active receptors function as a key mediator of endocrine, autonomic, behavioral, and immune responses to stress by coupling to G protein (Gs).&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/phys.org\/news\/2020-03-functional-corticotropin-releasing-factor-receptors.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Research: Structural and functional studies of corticotropin-releasing factor receptors<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: Phys.org&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>CRF1R and CRF2R, two members of class B G-protein-coupled receptors (GPCRs), are widely expressed in the central and peripheral nervous systems and activated by the corticoliberin family of peptide hormones&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-648364","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-phys-org"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/648364","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=648364"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/648364\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=648364"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=648364"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=648364"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}