{"id":661475,"date":"2020-07-21T08:11:05","date_gmt":"2020-07-21T12:11:05","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=661475"},"modified":"2020-07-21T08:11:05","modified_gmt":"2020-07-21T12:11:05","slug":"a-new-directed-evolution-technique-to-unlock-the-potential-of-xeno-nucleic-acids","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=661475","title":{"rendered":"A new directed evolution technique to unlock the potential of xeno-nucleic acids"},"content":{"rendered":"<p>As well as being required for some of the core techniques of molecular biology, reverse transcriptase (RT) enzymes have played a key role in synthetic genetics by enabling synthesis, replication, and evolution of xeno-nucleic acids (XNAs). However, for most XNA chemistries, no RT enzymes are available or existing enzymes have low activity. Philipp Holliger&#8217;s group, in the LMB&#8217;s PNAC Division, have developed a new directed evolution method to improve RT activity for any nucleic acid chemistry and discovered a new group of optimal RT enzymes.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/phys.org\/news\/2020-07-evolution-technique-potential-xeno-nucleic-acids.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">A new directed evolution technique to unlock the potential of xeno-nucleic acids<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: Phys.org&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As well as being required for some of the core techniques of molecular biology, reverse transcriptase (RT) enzymes have played a key role in synthetic genetics by enabling synthesis, replication,&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-661475","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-phys-org"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/661475","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=661475"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/661475\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=661475"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=661475"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=661475"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}