{"id":670658,"date":"2020-10-21T11:23:56","date_gmt":"2020-10-21T15:23:56","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=670658"},"modified":"2020-10-21T11:23:56","modified_gmt":"2020-10-21T15:23:56","slug":"transcription-factors-may-inadvertently-lock-in-dna-mistakes","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=670658","title":{"rendered":"Transcription factors may inadvertently lock in DNA mistakes"},"content":{"rendered":"<p>A team of researchers has found that transcription factors have a tendency to bind strongly to &#8216;mismatched&#8217; sections of DNA, i.e. sections of the genome that were not copied correctly. The strong binding of transcription factors to these mismatched sections of regulatory DNA might be a way in which random mutations become a problem that leads to disease, including cancer.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/www.sciencedaily.com\/releases\/2020\/10\/201021112356.htm\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Transcription factors may inadvertently lock in DNA mistakes<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: ScienceDaily&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of researchers has found that transcription factors have a tendency to bind strongly to &#8216;mismatched&#8217; sections of DNA, i.e. sections of the genome that were not copied correctly.&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-670658","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genaero"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/670658","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=670658"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/670658\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=670658"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=670658"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=670658"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}