{"id":685212,"date":"2021-03-25T13:04:58","date_gmt":"2021-03-25T17:04:58","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=685212"},"modified":"2021-03-25T13:04:58","modified_gmt":"2021-03-25T17:04:58","slug":"researchers-improve-plant-prime-editing-efficiency-with-optimized-pegrna-designs","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=685212","title":{"rendered":"Researchers improve plant prime editing efficiency with optimized pegRNA designs"},"content":{"rendered":"<p>Precision genome editing enables the precise modification of DNA in living cells, thus enabling a breadth of opportunities for plant breeding. Prime editors, developed by Prof. David R. Liu and his colleagues, permit the installation of desired edits in a programmable target site. They are composed of an engineered Cas9 nickase (H840A)-reverse transcriptase (RT) fusion protein and a prime editing guide RNA (pegRNA).&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/phys.org\/news\/2021-03-prime-efficiency-optimized-pegrna.html\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Researchers improve plant prime editing efficiency with optimized pegRNA designs<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: Phys.org&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Precision genome editing enables the precise modification of DNA in living cells, thus enabling a breadth of opportunities for plant breeding. Prime editors, developed by Prof. David R. Liu and&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[41],"tags":[],"class_list":["post-685212","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-phys-org"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/685212","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=685212"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/685212\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=685212"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=685212"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=685212"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}