{"id":698655,"date":"2021-08-10T16:13:49","date_gmt":"2021-08-10T20:13:49","guid":{"rendered":"https:\/\/spaceweekly.com\/?p=698655"},"modified":"2021-08-10T16:13:49","modified_gmt":"2021-08-10T20:13:49","slug":"frameshifting-therapy-for-mast-cell-cancers-reduces-size-spread-2","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=698655","title":{"rendered":"\u2018Frameshifting\u2019 therapy for mast cell cancers reduces size, spread"},"content":{"rendered":"<p>A potential new treatment for mast cell cancers reduces the number of mast cells by &#8216;mutating&#8217; the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene responsible for cell proliferation. The method, known as frameshifting, changes the pre-mRNA so that the mature mRNA is degraded and any protein produced from its instructions is altered and inert. In a mouse model, frameshifting directed at the c-KIT gene reduced mast cell tumor size and prevented infiltration into other organs.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/www.sciencedaily.com\/releases\/2021\/08\/210810161349.htm\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">\u2018Frameshifting\u2019 therapy for mast cell cancers reduces size, spread<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: ScienceDaily&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A potential new treatment for mast cell cancers reduces the number of mast cells by &#8216;mutating&#8217; the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene responsible&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-698655","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genaero"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/698655","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=698655"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/698655\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=698655"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=698655"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=698655"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}