{"id":699929,"date":"2021-08-24T10:41:33","date_gmt":"2021-08-24T14:41:33","guid":{"rendered":"http:\/\/spaceweekly.com\/?p=699929"},"modified":"2021-08-24T10:41:33","modified_gmt":"2021-08-24T14:41:33","slug":"age-related-decline-in-two-sirtuin-enzymes-alters-mitochondrial-dynamics-weakens-cardiac-contractions","status":"publish","type":"post","link":"https:\/\/spaceweekly.com\/?p=699929","title":{"rendered":"Age-related decline in two sirtuin enzymes alters mitochondrial dynamics, weakens cardiac contractions"},"content":{"rendered":"<p>The potential protective effect of sirtuin enzymes in age-related diseases, including cardiovascular diseases, remains an area of intense investigation. Now, researchers has determined that sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) levels decline in aging hearts, disrupting the ability of cardiac muscle cells (cardiomyocytes) to contract in response to ischemia-reperfusion injury.&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\n Click here for original story, <a href=\"https:\/\/www.sciencedaily.com\/releases\/2021\/08\/210824104133.htm\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Age-related decline in two sirtuin enzymes alters mitochondrial dynamics, weakens cardiac contractions<\/a>&#013;<br \/>\n&#013;<br \/>\n&#013;<br \/>\nSource: ScienceDaily&#013;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The potential protective effect of sirtuin enzymes in age-related diseases, including cardiovascular diseases, remains an area of intense investigation. Now, researchers has determined that sirtuin 1 (SIRT1) and sirtuin 3&hellip; <\/p>\n","protected":false},"author":1,"featured_media":615444,"comment_status":"false","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-699929","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genaero"],"_links":{"self":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/699929","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=699929"}],"version-history":[{"count":0,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/posts\/699929\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=\/wp\/v2\/media\/615444"}],"wp:attachment":[{"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=699929"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=699929"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/spaceweekly.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=699929"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}